CAS 128446-34-4 (2-Hydroxypropyl)-γ-Cyclodextrin

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  • Last update:

    2023-10-24 23:19

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Quick Details

 

Name:

CAS 128446-34-4 (2-Hydroxypropyl)-γ-Cyclodextrin

CAS Number:

128446-34-4

Abbreviation:

HPGCD

Cyclodextrin type:

Randomly substituted cyclodextrins, neutral

Quality:

Research grade,Technical Grade

Availability

In stock

 

Product Introduction

 

CAS 128446-34-4 (2-Hydroxypropyl)-γ-Cyclodextrin belongs to the class of cyclodextrin derivatives, which exhibit a greater extent of solubility in water compared to their parent compounds. It is widely used in parenteral formulations and solid dosage forms to aid in the improvement of their stability, dissolution, bioavailability, etc.

 

Chemical and Physical descripton

 

Average Molecular Formula

C48H80-nO40 · (C3H7O)n

Average Formula Weight

1297.2 + n·(58.1)

Appearance (Colour)

White to off white

Melting Point

>240°C (dec.)

Solubility
(in 100 cm3 solvent, at 25 °C)

Water: > 50gï¼›
Methanol: > 50gï¼›
Chloroform: < 1.0gï¼›

Applications

2-HYDROXYPROPYL .GAMMA.-CYCLODEXTRIN is used in the solubilization of macromolecules and in cell culture applications. Similar to beta Cyclodextrin ,but it can work with larger molecules.

 

Specification

 

ITEMS

CRITERIA

Appearance

White or almost white powder;Odorless, slightly sweet;Freely soluble in water,soluble in ethanol,almost insoluble in acetone .

Water solution pH

pH5.0~8.5

Light-absorbing impurities

max. 0.5 (230 – 660 nm)

Water

≤10.0%

Alpha Cyclodextrin

≤1.5%

Residue on ignition

≤0.2%

Heavy Metal

≤10ppm

Propylene glycol

≤0.5%

Assay

≥98%

Hydroxypropoxyl content

17.5%~29.1%

The total aerobic microbial count

≤103cfu/g

The total combined moulds and yeasts count

≤102cfu/g

Escherichia coli

Absence

Bacterial Endotoxins Test

According to preparation needs <0.01EU/mg

 

Application

 

CAS 128446-34-4 (2-Hydroxypropyl)-γ-Cyclodextrin only for reagent and laboratory purposes, not for human use;

Laboratory chemicals, manufacture of substances,solubilizer, chiral selectorï¼›

Solvent Enhancer, Embedding Agent, Analytical Reagentï¼›

 

Packing & Storage

 

On-demand pack size is available without surcharge.

This Product is available in multi-kilograms pack size, such as: 1kg,5kg,10kg

★Internal packing: PE bag and aluminum foil bag

★Outer packing: carton or drum.

★Storage:Preserve well-closed containers protect from moisture.

Shipping Information

★Tariff No.:3505100000

 

Safety Features

 

Description of first aid measures for (2-Hydroxypropyl)-g-cyclodextrin

General advice

1

If inhaled

Remove to fresh air and monitor breathing. If breathing becomes difficult, give oxygen. If breathing stops, give artificial respiration. Consult a doctor.

2

In case of skin contact

Immediately wash skin with copious amounts of soap and water for at least 15 minutes. Remove contaminated clothing and shoes and wash before reuse. Consult a doctor.

3

In case of eye contact

Flush with copious amounts of water for at least 15 minutes. Consult a doctor.

4

If swallowed

Rinse mouth with water. Do not induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person. Consult a doctor.

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